Fig. 1.
The initial screening of the PS-SPCLs for peptides stimulating superoxide generation of human monocytes.
Each panel shows the results obtained with the peptide pools with known amino acids at each of the 6 positions of the hexapeptide. The 6 positions were individually defined (eg, O1, O2) by one of the 19 L-amino acids. The remaining 5 positions consist of mixtures (X) of the 19 L-amino acids (except for cysteine). Human monocytes (9 × 105/100 μL) were used for each assay. Cytochrome c reduction was monitored as described in “Materials and methods.” The results represent 1 of 4 independent experiments.
