Fig. 1.
Fig. 1. Level of hFVIII antigen and hFVIII inhibitor titer in C57BL mice (n = 3) after administration of rAAV and BDD-hFVIII. / Solid line indicates hFVIII antigen level; and broken line, anti-BDD-hFVIII inhibitor titer. The ELISA standard curve for hFVIII was obtained by using pooled normal human plasma diluted in either barbital-buffered saline or mouse plasma. Values (± SEM) represent the averages of three animals.

Level of hFVIII antigen and hFVIII inhibitor titer in C57BL mice (n = 3) after administration of rAAV and BDD-hFVIII.

Solid line indicates hFVIII antigen level; and broken line, anti-BDD-hFVIII inhibitor titer. The ELISA standard curve for hFVIII was obtained by using pooled normal human plasma diluted in either barbital-buffered saline or mouse plasma. Values (± SEM) represent the averages of three animals.

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