Growth and replication of CFU-GM.

(A) Growth rates of CFU-GM colonies grown from marrow ofp16^INK4a knockout (−/−) and intact (+/+) mice. n = number of colonies analyzed in each group. (B) Replicative capacity of CFU-GM, as reflected by the AUC, grown from marrow ofp16^INK4a knockout (−/−) and intact (+/+) mice. n = 3 for each group.