Fig. 5.
![Fig. 5. Whole blood coagulation and 7E3. / Comparison of whole blood coagulation in the absence (▪) and presence (●) of 7E3 (10 μg/mL). Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panels C and D platelet activation (osteonectin [ON] and PF4 release, respectively). Arrow “a” indicates clotting times for the control experiment, arrow “b” for the 7E3 experiment. Upper lane in panel D represents control experiment and lower lane represents 7E3 experiment.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/97/8/10.1182_blood.v97.8.2314/5/h80810935005.jpeg?Expires=1722695232&Signature=00wddy3x47mLyxzMO768btht2KatYKzvGiTss69FgDalGNyN0jbYlBgjGe3GGSIWz57BPK1HKAnGASQrG1Yevb1rkwdc5itMRzKeWRJ1SZTFAX6lSNJjB48DG~KP00F4tk~oMdoO6DKUN3LDL4sHz0XaTUrJeWiRADp5u8kVfnWIOXmmEBzJ1SLnsEmRtcUmIEewnTjuODpo9RKNUH69f7nL8J34PVjUTLtSTLigIWImbyLLdheYSxSLoS6gqDTQ3aWvrEkQz8XQ5EC56SvrNuSO87ReOU-KasSGDjpjgOH1P~eHgbmP5hOcKjahGpDj2k3tcfcJmcNEcQJuOSx6gA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Whole blood coagulation and 7E3.
Comparison of whole blood coagulation in the absence (▪) and presence (●) of 7E3 (10 μg/mL). Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panels C and D platelet activation (osteonectin [ON] and PF4 release, respectively). Arrow “a” indicates clotting times for the control experiment, arrow “b” for the 7E3 experiment. Upper lane in panel D represents control experiment and lower lane represents 7E3 experiment.
