Thrombin (TAT) generation in whole blood initiated by 200 pM TF.

Coagulation was initiated by relipidated TF as described in “Materials and methods” in the absence of any adjuvant (▪), in the presence of 5 μM Integrilin (▴) and in the presence of 10 μg/mL Reopro (●). Arrow “a” indicates clotting time for control experiment, arrow “b” for Integrilin experiment, and arrow “c” for Reopro experiment.