Fig. 3.
Fig. 3. Whole blood coagulation and ASA. / Comparison of whole blood coagulation before (▪) and after (●) administration of ASA, 2 × 325 mg/d for 3 consecutive days. Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panel C platelet activation (osteonectin [ON] release). Arrow “a” indicates clotting times before ASA administration, arrow “b” after.

Whole blood coagulation and ASA.

Comparison of whole blood coagulation before (▪) and after (●) administration of ASA, 2 × 325 mg/d for 3 consecutive days. Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panel C platelet activation (osteonectin [ON] release). Arrow “a” indicates clotting times before ASA administration, arrow “b” after.

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