Fig. 2.
Fig. 2. Whole blood coagulation and PGE1. / Comparison of whole blood coagulation in the absence (▪) and presence (●) of 5 μM PGE1. Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panels C and D platelet activation (osteonectin [ON] and PF4 release, respectively). Arrow “a” indicates clotting times for the control experiment, arrow “b” for the PGE1 experiment. Upper lane in panel D represents control experiment and lower lane represents PGE1experiment.

Whole blood coagulation and PGE1.

Comparison of whole blood coagulation in the absence (▪) and presence (●) of 5 μM PGE1. Coagulation was initiated in whole blood by 25 pM relipidated TF as described in “Materials and methods.” Panel A represents thrombin (TAT) generation, panel B fibrin (FPA) formation, and panels C and D platelet activation (osteonectin [ON] and PF4 release, respectively). Arrow “a” indicates clotting times for the control experiment, arrow “b” for the PGE1 experiment. Upper lane in panel D represents control experiment and lower lane represents PGE1experiment.

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