Time course of approximately 70-saccharide (H₇₀) high-affinity heparin-catalyzed inhibition of factor Xa or prothrombinase by the mutant of antithrombin.

(A) Conditions and symbols are the same as those described for Figure3A, except that 1 nM H₇₀ was used in the reactions. (B) The same as Figure 3B except that 1 nM H₇₀ in the absence (○) or the presence of 50 μM PC/PS (●) and 100 nM H₇₀ in the presence of 50 μM PC/PS plus 5 nM factor Va (fully assembled prothrombinase) (■) was used in the reactions.