Fig. 1.
Fig. 1. FANCC−/− MEFs are hypersensitive to apoptosis induced by IFN-γ and dsRNA. / Equivalent numbers of cells were incubated with murine recombinant IFN-γ (10 ng/mL) for 15 hours, followed by transfection with or without 100 μg/mL of poly(I).poly(C) in the presence of LipofectAmine. Mock exposed cells were incubated with LipofectAmine only. After 24 hours, cells were subjected to viability determination by trypan blue exclusion assay. ▧, FANCC−/−; ■, FANCC+/+. Data are the mean ± standard deviations of triplicate determinations.

FANCC−/− MEFs are hypersensitive to apoptosis induced by IFN-γ and dsRNA.

Equivalent numbers of cells were incubated with murine recombinant IFN-γ (10 ng/mL) for 15 hours, followed by transfection with or without 100 μg/mL of poly(I).poly(C) in the presence of LipofectAmine. Mock exposed cells were incubated with LipofectAmine only. After 24 hours, cells were subjected to viability determination by trypan blue exclusion assay. ▧, FANCC−/−; ■, FANCC+/+. Data are the mean ± standard deviations of triplicate determinations.

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