Thrombin activation of human platelets produced by engrafted NOD/SCID mice.

Shown are dot blots of human platelets from transplanted mice before and after thrombin stimulation. On the x-axis is FITC–anti-CD41a, which is present on all human platelets and not on murine platelets. The y-axis is PE–anti-CD62, which is expressed only on activated platelets.