American Society of Hematology

Fig. 7.

$Fig. 7. Effect of BCR-ABL expression on γ irradiation-induced apoptosis. / UT-7 and BCR-ABL transfected cells were irradiated at 0, 2, 5, and 10 Gy and collected 24 hours later. Histograms show the average and SD for at least 3 independent experiments evaluating the apoptotic fractions quantified by flow cytometric analysis of PI iodide and annexin V-FITC–stained cells. The clones with the highest levels of BCR-ABL (UT-7-8/1 and UT-7/9) were refractory to radioinduced apoptosis.$

Effect of BCR-ABL expression on γ irradiation-induced apoptosis.

UT-7 and BCR-ABL transfected cells were irradiated at 0, 2, 5, and 10 Gy and collected 24 hours later. Histograms show the average and SD for at least 3 independent experiments evaluating the apoptotic fractions quantified by flow cytometric analysis of PI iodide and annexin V-FITC–stained cells. The clones with the highest levels of BCR-ABL (UT-7-8/1 and UT-7/9) were refractory to radioinduced apoptosis.

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