Delayed UVB-induced caspases 9 and 3 activation and bcl2 up-regulation in MDCs.

(A) IDCs and MDCs from the same donor were exposed to 1 J/cm² UVB and analyzed by Western blotting at the time points indicated for caspase 9 (pro-caspase9) and caspase 3 processing. (B) Expression of bcl2, bclxL, and bax was investigated in IDCs and MDCs from the same donor. Representative blots from 1 of 3 donors giving similar results are shown. (C) Time course of UVB-induced ΔΨm dissipation in IDCs and MDCs derived from the same donor. ○ and ▵, untreated cells; ● and ▴, UVB-treated cells; ▴ and ▵, IDCs; ● and ○, MDCs. Means ± SD from 4 experiments are shown.