Chemokine gene expression in HD lymph nodes.

(A) Percentage of cells expressing RANTES, MCP-1, MIP-1α, and MIP-1β. Results represent the mean (± SE) from 19 cases hybridized with specific antisense probes and evaluated quantitatively. (B) Representative in situ gene expression left: All the chemokines are expressed in the nonneoplastic leukocytic infiltrates of HD but not in H-RS cells (arrows). The sense probe controls for MCP-1 and RANTES are shown. The sense probe controls for MIP-1α and MIP-1β were comparable (data not shown).