Effects of 5-HT on the concentration of functionally active PAI-1 in the medium.

(A) Dose-dependent effects of 5-HT. Each bar represents the mean ± SEM of 3 independent experiments (*P < .05 versus vehicle-treated controls). (B) Time-dependent effects of 5-HT. ▪, 5-HT, 10 μM; ■, vehicle.