Effects of 5-HT on TF and TFPI mRNA expression.

(A) Dose-dependent effects of 5-HT. (B) Time-dependent effects of 5-HT. TF and TFPI mRNA expression was normalized to GAPDH mRNA expression. Relative TF mRNA expression, ▪; TFPI, ■. Each bar represents the mean ± SEM of 3 independent experiments (*P < .05 versus vehicle-treated controls). Relative TF and TFPI mRNA expressions represent the fold increase in normalized TF and TFPI mRNA expression compared to vehicle-treated controls, respectively.