Fig. 3.
The inhibition of cell growth by Rituxan monomers and homodimers.
DHL-4 cells (2 × 105/mL) were cultured in CM in the presence of different concentrations (1 to 100 μg/mL) of Rituxan monomers (●), IgG homodimers (○), or F(ab′)2 homodimers (▾) or in CM (▿) (control) for 6 days, and the growth was compared with that of untreated cells. Samples of cells were taken daily and counted. The viability was determined by trypan blue exclusion. Cell concentrations were plotted against time in culture, and the growth index was determined. This is 1 of 2 experiments carried out.
