Fig. 2.
Expression of cdc2 and cell cycle arrest of human myeloid cell line, MO7e, after MTD.
Scatter density diagrams of bivariate cell cycle analysis of vector control cells (LXSN; A,C) and p21 antisense (AS21; B,D) are shown. Day 3 cell cultures were treated for 24 hours with 15 μg/mL nocodazole (C,D) or control diluent (A,B). The 2N (G0/G1) and 4N (G2/M) DNA content is indicated along with the percentages of cells in different cell cycle phases. Data are representative of at least 6 separate experiments done in triplicate.
