Fig. 1.
NO donors induce HIF-1α accumulation.
LLC-PK1 cells were stimulated with 100 μM Dea-NO, GSNO, spermine-NO, Deta-NO, or vehicle for the times indicated. Accumulation of HIF-1α was determined by Western blot analysis as outlined in “Materials and methods.” Blots are representative for at least 3 independent experiments.
