Fig. 1.
Generation of GM-CSF/IL3–deficient mice.
(A) Structure of the wild-type and targeted GM-CSF/IL-3 loci. (B). Genotyping of wild-type, heterozygous, and homozygous doubly deficient animals. Tail DNA was digested with either HindIII orBamHI and characterized by Southern analysis using the indicated probes.