EFS for all children treated on 4 consecutive DFCI ALL Consortium protocols.

Consortium protocols shown are: 81-01 (1981-1985), 85-01 (1985-1987), 87-01 (1987-1991), and 91-01 (1991-1995). There was significant difference (P = .03) in EFS when comparing all 4 protocols, with most favorable results observed on Protocol 91-01 (5-year EFS ± SE, 83% ± 2%).