Northern blot analysis of the TEL-Syk transcript.

The TEL probe T2, located 5′ of the translocation breakpoint, detected wild-type 6.5-, 4.5-, and 2.4-kb transcripts present in HL-60; novel 4.2- and 1.8-kb transcripts were identified in the patient's mononuclear cells with t(9;12). The Syk probe S, located 3′ of the translocation breakpoint, detected the same 4.2- and 1.8-kb transcripts in the patient's cells, whereas 5.6- and 2.8-kb transcripts were detected in HL-60.