CD4⁺ or CD8⁺ T lymphocyte populations in peripheral blood and spleen from BALB/c mice after BMT.

Percentages of CD4⁺ or CD8⁺ T lymphocytes in peripheral blood or spleen from BALB/c mice given 10 Gy TBI followed by 2 × 10⁷ BM cells and 1 × 10⁷ (Ai,Bi) or 5 × 10⁷ (Aii, Bii) spleen cells from C57BL/6 (GVHD; ▩), 2 × 10⁷ BM cells and 1 × 10⁷(Ai,Bi) or 5 × 10⁷ (Aii,Bii) spleen cells from C57BL/6 and daily oral administration of TAK-603 (GVHD+TAK; ▨) and 2 × 10⁷ BM cells and 1 × 10⁷ (Ai,Bi) or 5 × 10⁷ (Aii,Bii) spleen cells from BALB/c mice (syngeneic; ░) on day 6 after transplantation. The data represent mean ± SD. *P < .01; **P < .05.