Fig. 2.
Histopathologic examination.
Induction of lethal acute GVHD and administration of TAK-603 were performed as described in “Materials and methods.” On day 6, 3 mice from each of the 6 groups were killed. Paraffin sections of the skin, liver, and small intestine were stained by hematoxylin and eosin (original magnification: A, × 200; B, × 400. Intestine (i): intestine from BALB/c mice receiving 2 × 107 nucleated BM cells and 1 × 107 nucleated spleen cells. Intestine (ii): intestine from BALB/c mice receiving 2 × 107nucleated BM cells and 5 × 107 nucleated spleen cells.
