Sequence of the sH-IgM.22 Vλ.

The sequence is aligned according to the numbering system of human Vλ sequences in Kabat et al.26 Vλ of sH-IgM.22 is a member of the lambda subgroup I. The underlined amino acids have been confirmed by protein sequencing. Amino acid sequence corresponds to sH-IgM.22 nucleotide sequence. sH-IgM.22 Vλ type I and II sequences are represented only with nucleotides that differ from IGLV1-51*01 and IGLJ3*01 germline sequences.27 Two amino acid replacements in the protein sequence of SH-IgM.22 Vλ type II are printed in parentheses. Reference for germline sequences on both figures are IMGT.27