Fig. 4.
Fig. 4. Effects of As2O3 on tRA-induced PML-RARα degradation and gene modulation. / (A) PML-RARα and RARα protein levels. Anti-RARα antibody was used to detect PML-RARα and RARα. (B) Northern blot analysis of tRA inducible gene expression. NB4 cells were treated with different concentrations of tRA with or without 0.5 μM As2O3 for 4 days.

Effects of As2O3 on tRA-induced PML-RARα degradation and gene modulation.

(A) PML-RARα and RARα protein levels. Anti-RARα antibody was used to detect PML-RARα and RARα. (B) Northern blot analysis of tRA inducible gene expression. NB4 cells were treated with different concentrations of tRA with or without 0.5 μM As2O3 for 4 days.

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