BAY 36-1677 does not affect the growth of endothelial cells and fibroblasts.

Native IL-4 and BAY 36-1677, both at 100 ng/mL, were added to cultures of HUVECs (top panels) for 1 week and skin fibroblasts (bottom panels) for 3 weeks. HUVECs were labeled with a mixture of antivimentin antibody and actin-binding phalloidin after culture. Native IL-4 impaired the growth of endothelial cells and stimulated fibroblast proliferation.