BAY 36-1677 confers a growth advantage to normal hematopoietic cells.

Normal CD34⁺ cells were mixed with leukemic KOPN57bi cells (20%, top; 5%, bottom) and cultures for 7 days on stroma. Flow cytometric density plots illustrate that in control cultures (left panels), proportions of ALL cells (identified by their high CD19 and CD10 expression; circles) increased, whereas these decreased in the presence of BAY 36-1677 (25 ng/mL; right panels).