Distribution of clone sizes generated by different phenotypes of single CML cells cultured in growth factor–supplemented SFM.

CD34⁺CD38⁻ (▪), CD34⁺CD38⁺ (■), and CD34⁻ (░) cells were cultured for 10 days in the presence of FL, SF, IL-3, IL-6, and G-CSF. The numbers on the abscissa indicate the minimum number of cells per clone for clones whose sizes ranged up to the next number shown. Results are from a representative experiment with cells from patient 2.