Fig. 1.
Fig. 1. Genomic PCR for the Flt3/ITD. / Genomic DNA prepared from diagnostic marrow specimens were PCR amplified and resolved on polyacrylamide gel. C, non-nucleic acid control; NL, normal marrow control; 1-9, samples from 9 different pediatric patients. High-molecular weight bands in lanes 4 and 7 represent the Flt3/ITD. Patient sample in lane 4 does not have a normal Flt3 band. This patient was previously shown to have a loss of heterozygosity (LOH) of chromosome 13 at the region of theFlt3 gene. Arrow points to the normal Flt3 gene product.

Genomic PCR for the Flt3/ITD.

Genomic DNA prepared from diagnostic marrow specimens were PCR amplified and resolved on polyacrylamide gel. C, non-nucleic acid control; NL, normal marrow control; 1-9, samples from 9 different pediatric patients. High-molecular weight bands in lanes 4 and 7 represent the Flt3/ITD. Patient sample in lane 4 does not have a normal Flt3 band. This patient was previously shown to have a loss of heterozygosity (LOH) of chromosome 13 at the region of theFlt3 gene. Arrow points to the normal Flt3 gene product.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal