Fig. 4.
Fig. 4. Inhibition of NF-κB sensitizes HD cells to CD30-induced death. / L428 cells were transfected with 5 μg of a GFP plasmid, along with 10 μg of either a control plasmid (pEBB) or a superdominant (sd) IκBα plasmid as indicated. Cells were incubated with the immobilized CD30 agonistic antibodies M67 or isotype control antibodies for 18 hours before measuring for viability as described in “Materials and methods.”

Inhibition of NF-κB sensitizes HD cells to CD30-induced death.

L428 cells were transfected with 5 μg of a GFP plasmid, along with 10 μg of either a control plasmid (pEBB) or a superdominant (sd) IκBα plasmid as indicated. Cells were incubated with the immobilized CD30 agonistic antibodies M67 or isotype control antibodies for 18 hours before measuring for viability as described in “Materials and methods.”

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