American Society of Hematology

Fig. 2.

$Fig. 2. Long-term follow-up of hG6PD expression in mouse peripheral blood RBCs. / Each line represents one mouse. (A) MMb2-G6PD mice. (B) MPSV-G6PD (…) and MPSVb2-G6PD (—) mice. In each panel the fractional number indicates the number of mice still expressing at 8 to 20 months/number of mice originally expressing at 1 month. Mice marked with asterisk received BM cells transduced by coculture; all others received BM cells transduced with VSV-G supernatants. In each panel a horizontal line is traced at 17% of the total G6PD activity, which is equivalent to 20% of the endogenous murine activity (see text). The relative quantitation of hG6PD expression was obtained by cellulose acetate gel electrophoresis.$

Long-term follow-up of hG6PD expression in mouse peripheral blood RBCs.

Each line represents one mouse. (A) MMb2-G6PD mice. (B) MPSV-G6PD (…) and MPSVb2-G6PD (—) mice. In each panel the fractional number indicates the number of mice still expressing at 8 to 20 months/number of mice originally expressing at 1 month. Mice marked with asterisk received BM cells transduced by coculture; all others received BM cells transduced with VSV-G supernatants. In each panel a horizontal line is traced at 17% of the total G6PD activity, which is equivalent to 20% of the endogenous murine activity (see text). The relative quantitation of hG6PD expression was obtained by cellulose acetate gel electrophoresis.

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