Model of

cbfb function in embryonic hematopoiesis. Based on results described in this study and published earlier,cbfb can be placed at the hematopoietic stem cell (HSC) level, similar to scl, whereas gata-1 is involved in later steps during hematopoiesis. Previous studies and expression pattern ofcbfb reported here also suggest that cbfb is expressed in hemangioblasts and might play a role in angiogenesis. RBC indicates red blood cell; EC, endothelial cell.