FcγRIIA tg mice experience more severe anti-CD9–mediated thrombocytopenia.

The bar graph depicts average nadir counts (± SD) from the FcγRIIA tg mice, strain-matched wild-type controls, and FcR γ-KO mice all treated with 50 μg rat antimouse CD9 antibody by IP injection. Control counts represent the combined nadir counts from all lines given identical injections with an equal volume of sterile saline. The FcγRIIA tg mouse nadir counts were significantly different from control, γ-KO, and wild-type mouse nadir counts by analysis of variance (*, P < 0.05).