Fig. 4.
Relationship between expression of Apaf-1 or procaspase-2, -3, -7, -8, or -9 and response of previously untreated patients with AML to induction chemotherapy.

Relationship between expression of Apaf-1 or procaspase-2, -3, -7, -8, or -9 and response of previously untreated patients with AML to induction chemotherapy.

From the blots shown in Figure 2, as well as 3 additional sets of blots containing 29 more AML samples, relative levels of Apaf-1 and the indicated procaspases were quantitated. The relationship between relative polypeptide content and response of patients to the first cycle of induction chemotherapy is indicated. Bars represent median peptide levels.

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