Fig. 6.
VLA-5− myeloma plasma cells express significantly higher levels of CD126 than VLA-5+ plasma cells.

VLA-5 myeloma plasma cells express significantly higher levels of CD126 than VLA-5+ plasma cells.

However, cycling (Ki-67+) plasma cells are VLA-5 but express lower levels of CD126 than noncycling plasma cells. Box and whisker plots showing the minimum; 25th, 50th, and 75th percentiles; and maximum expression of CD126 (IL-6 receptor alpha-chain) by (A) VLA-5+ and VLA-5 myeloma plasma cells and (B) Ki-67 and Ki-67+ myeloma plasma cells. Values shown are the K-S D values for the separation of test (CD126-PE fluorescence) and control (CD3-PE fluorescence) cumulative frequencies. P values shown are for the difference in expression levels between VLA-5+ versus VLA-5, and Ki-67+ versus Ki-67plasma cells, respectively (Mann-Whitney U test).

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