Immunofluorescence microscopy of platelet adhesion.

Immunofluorescence microscopy shows adhering platelets (in green) on endothelial cells (in red). (A) Control shows platelet binding to unstimulated endothelial cells, with a few adhering platelets. (B) An increased number of adhering platelets on VEGF-stimulated endothelial cells is depicted compared to the unstimulated control in panel A. Magnification (40 ×) shows that most platelets adhere to the endothelial cells and to a lesser extent to the extracellular matrix.