Fig. 7.
Southern blot analysis of the Bcl-2 locus in p185ΔBCR/Bcl-2 clones before injection in SCID mice and in leukemic cells recovered from the spleen.
Southern blot of genomic DNA from p185ΔBCR 32Dc13 clones (left panel), p185ΔBCR/Bcl-2 clones (middle panel), and p185ΔBCR/Bcl-2 clones recovered from the spleen of leukemic mice (right panel). Genomic DNA was digested with HindIII, BamHI, orXbaI (from left to right), electrophoresed on a 0.8% agarose gel, transferred to nylon membranes, and hybridized to a32P-labeled Bcl-2 fragment.
