Fig. 2.
Ligand-independent 3H thymidine incorporation by Flt3-ITD mutants.
Cells were starved for 12 hours from IL-3 and serum and stimulated with FL (100 ng/mL or indicated concentrations), IL-3 (10 ng/mL), or no cytokine. Data are shown as percentage of thymidine incorporation compared with thymidine incorporation of the respective cell line under IL-3 stimulation. Note the different scale of the y-axis in the 2 diagrams of B.
