Survival of mice challenged with 38C13 tumor cells.

(A) C3H/HeN mice were immunized twice subcutaneously with 50 μg of the tested Id fusion proteins or PBS alone and intraperitoneally challenged with 38C13 cells 2 weeks after the second immunization. The percentage of survivors in each group was recorded. (B) C3H/HeN mice were immunized twice intraperitoneally with 10 μg of the tested Id fusion proteins or PBS alone and subcutaneously challenged with 38C13 cells 2 weeks after the second immunization. The mean tumor volume of mice bearing a measurable tumor mass in each group was calculated. SD (bars) are only given at day 24 for clarity. The ratio of animals in each group that succumbed to tumor death is indicated.