Distribution of mob Fe in relation to age and sex.

Mob Fe is plotted here as a function of age and sex for C282Y homozygotes. Overall, women had lower degrees of iron loading than men (median = 3.4 g for women; median = 4.6 g for men). In this asymptomatic population of men and women identified by screening, there was no correlation between age and degree of iron loading (r = 0.22 for men; r = −0.01 for women). The mean age for patients with greater than 4 g mob Fe was 48.9 years, and the mean age for patients with between 1.5 and 4 g mob Fe was 51.2 years.