Vessel density analysis using CD34 mAb staining.

(Ai) Representative CD34 staining of CLL node. (Aii) CD34 staining of normal node where interfollicular (IF) areas are vascularized, and follicular (F) areas display very little vascularization. Original magnification, × 10. (B) Quantitative analysis shows the higher vessel density in CLL nodes (n = 3) compared with follicular B-cell areas of normal nodes (n = 3).