Coagulation profiles of fibrinogen.

Normal plasma and plasma from the propositus, used at the same immunologic concentration of fibrinogen (4 mg/mL), were diluted in 150 mmol/L NaCl. After thrombin addition, the optical density (OD) was recorded at 350 nm. Normal plasma diluted to 1:10 (○), plasma from the propositus diluted to 1:10 (●), and plasma from the propositus diluted to 1:3 (▴).