IFN-γ production and CD69 up-regulation in HIV-specific CD8 T cells is IL-2 dependent in some seropositive subjects.

CD8 T cells from seropositive subjects were stimulated with uniformly HIV-infected CD4 T cells, as in Figure 1. CD8 T cells stimulated with infected CD4 T-cell blasts in the presence (▧) or absence (░) of IL-2 were stained for IFN-γ (A) and CD69 (B). Data shown are the results after subtracting the values obtained with uninfected CD4 blasts under the same culture conditions.