American Society of Hematology

Fig. 6.

$Fig. 6. Effect of antioxidant treatments on fraction 7 induction of surface tissue factor pathway activity. / Fraction 7 (see Figure 5) at a level equivalent to 400 μg protein of intact oxidized LDL per milliliter was added to rat aortic smooth muscle cells for 4 hours before tissue factor assessment. Cells were pretreated with either DPPD (1 μmol/L), ebselen (10 μmol/L), Tiron (10 mmol/L), or desferoximine (3 mmol/L) overnight before and during the addition of fraction 7. NT indicates no treatment (solvent) control. Data represent means ± SD of 4 wells per treatment.$

Effect of antioxidant treatments on fraction 7 induction of surface tissue factor pathway activity.

Fraction 7 (see Figure 5) at a level equivalent to 400 μg protein of intact oxidized LDL per milliliter was added to rat aortic smooth muscle cells for 4 hours before tissue factor assessment. Cells were pretreated with either DPPD (1 μmol/L), ebselen (10 μmol/L), Tiron (10 mmol/L), or desferoximine (3 mmol/L) overnight before and during the addition of fraction 7. NT indicates no treatment (solvent) control. Data represent means ± SD of 4 wells per treatment.

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