Fig. 6.
Differential recruitment of the coactivator ACTR by wild-type and mutant PML/RARα fusion proteins on a DR5 RARE in gel mobility shift assay.
Interaction of ACTR with wild-type and mutant PML/RARα S-form (A) and L-form (B). In vitro translated PML/RARα fusion proteins were coincubated with the [32P]-labeled DR5 RARE, along with bacterially expressed GST-ACTR-RID in the presence of increasing concentrations of RA. The position of the complex shifted by ACTR indicated.
