Up-regulation of surface monocyte CD11b by cross-linking of CD36.

One hour after treatment with a 1-μg/mL dose of LPS or cross-linking of surface CD36 (FA6-152), HLA-DR (BL2), FcγRIII (3G8), CD18 (7E4), or CD49d (hp2.1), monocytes were washed extensively and evaluated for surface expression of CD11b as described in “Materials and methods.” Points are taken in triplicate and are representative of results obtained in 4 separate experiments. MCF indicates median channel fluoresence; **, P < .01; ***,P < .001 vs mock–cross-linked cells (ANOVA with post hoc Tukey).