American Society of Hematology

Fig. 2.

$Fig. 2. Pepstatin A blocks CD40-mediated TRAF3 depletion and NF-κB activation. / Western blot analysis of cytosolic TRAF3. KMH2 cells were stimulated with CD40L for 45 minutes in the presence of the indicated concentrations of pepstatin A (A), or ritonavir or indinavir (B). The cytoplasmic fractions were analyzed by Western blotting with anti-TRAF3 antibody. The arrow indicates the position of TRAF3. Pep indicates pepstatin A; R, ritonavir; I, indinavir.$

Pepstatin A blocks CD40-mediated TRAF3 depletion and NF-κB activation.

Western blot analysis of cytosolic TRAF3. KMH2 cells were stimulated with CD40L for 45 minutes in the presence of the indicated concentrations of pepstatin A (A), or ritonavir or indinavir (B). The cytoplasmic fractions were analyzed by Western blotting with anti-TRAF3 antibody. The arrow indicates the position of TRAF3. Pep indicates pepstatin A; R, ritonavir; I, indinavir.

This Feature Is Available To Subscribers Only