Lip-clod inhibits the Ab-induced thrombocytopenia in a dose-dependent manner.

Five groups of 6 BALB/c mice were injected intravenously with 200μL of saline, or different amounts of lip-clod (1:1 ; 1:4 ; 1:8 or 1:32). After this treatment the animals were injected at 24, 48, 72, 96, and 120 hours with a daily intraperitoneal dose of 25μL of Ab. The mice were bled daily for platelet counting as described in “Materials and methods.” Bars represent mean ± SEM *P < .0001, significantly different from the control Ab-treated group at 24, 48, 72, 96, and 120 hours, Bonferroni test (2-tailed).