Effect of rabbit ant-mouse platelet antiserum on the platelet count.

Two groups of 6 BALB/c mice were injected intraperitoneally with 25 μL (100 μL dilution 1:4) of Ab. One of them received a single dose (time = 0) (■), and the other received a daily dose of Ab (▪). Control mice were injected with 25 μL of saline (●). Control and Ab-treated groups were bled at 4, 24, 48, 72, and 96 hours for platelet count. The arrows represent the time (after bleeding) at which the Ab was administered. Values represent mean ± SEM. *P < .0001, significantly different from control group at 4, 24, 48, 72, and 96 hours, Bonferroni test (2-tailed).