Deletion series of transgenic constructs.

This series analyzed various genomic segments of the c-fesgene for LCR activity. The columns at right summarize the data obtained for each construct. Events represents the number of founders generated and analyzed. Copy number range shows the lowest and highest number of transgene copies for each construct. A Y in the integration-independent column indicates that all of the founders expressed the transgene. A Y in the copy-number–dependent column indicates that all of the founders expressed the human gene at the expected levels in all tissues assayed. A Y in the ectopic column indicates that human c-fes mRNA detected was above the level expected (on the basis of copy number) in at least one of the tissues assayed. The last column lists the tissues where ectopic c-fes expression was observed. *Shows that a single founder was analyzed.